]> Oldham CE, Powell RS, Williams AB,et al. Volume 1 Issue 1 2581-4745 10.31531/2581-4745.1000106 Alzheimers disease AD is not only the most common neurodegenerative disease but is also currently incurable Proprotein convertase subtilisinkexin9 PCSK9 is an indirect regulator of plasma low density lipoprotein LDL levels controlling LDL receptor expression at the plasma membrane PCSK9 also appears to regulate the development of glucose intolerance insulin resistance abdominal obesity inflammation and hypertension conditions that have been identified as risk factors for AD PCSK9 levels also depend on age sex and ethnic background factors associated with AD Herein we will review indirect evidence that suggests a link between PCSK9 levels and AD All Published Work is Licensed under a creative commons attribution 4.0 international license 2024