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<title>International-Journal-of-Biomedical-Investigation-ISSUE VOLUME Volume 1 ISSUE Issue 3</title>
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International-Journal-of-Biomedical-Investigation: VOLUME Volume 1 ISSUE Issue 3, Sept-Dec 2018
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<title>International-Journal-of-Biomedical-Investigation-ISSUE VOLUME Volume 1 ISSUE Issue 3</title>
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		<title>Knowledge-About-Oral-Cancer-in-Older-Adults-at-the-Wajay-Grandparents-House</title>
		<pubDate>28-Dec-2018</pubDate>
<link>http://ijbi.edwiserinternational.com/admin/uploads/r0jnxB.pdf</link>
		<author>Quintero-OMS-Hernandez-DKA-Borrego-AP-et-al-</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[Introduction: One of the causes of aging in people is associated with the appearance or increase of stomatological conditions, within them oral cancer is the highest incidence in the elderly population and its prevention plays an important role in primary health care.Objective: to determine knowledge about oral cancer in older adults at the Wajay Grandparents House.Materials and Methods: A cross-sectional descriptive study was carried out from February to April 2015 to 45 elderly adults belonging to the Wajay grandparents home of the polyclinic Dr. Mario Muoz Monroy, a questionnaire was created by the researcher where the following variables: age, sex, knowledge about cancer risk factors, knowledge about oral self-examination, frequency, signs and symptoms of alarm and where to go if changes are observed, and the level of knowledge about oral cancer of the respondents.Results: The predominant gender was male (53.8) and the age of 60-74 years (44.4%), most of the geronants had in the knowledge about smoking as a fundamental risk factor (62.2%) more than half of the population does not knowing the Oral Cancer Detection Program (82.2%), only the general level of knowledge was poor (48.8%). Conclusion: The male group aged 60-74 years predominated and there was a poor level of knowledge about oral cancer in the studied population.]]>}</description>
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		<title>Analysis-of-Gene-Expression-and-Neuronal-Phenotype-in-Neuroscreen-1-NS-1-Cells</title>
		<pubDate>22-Dec-2018</pubDate>
<link>http://ijbi.edwiserinternational.com/admin/uploads/1a4FZW.pdf</link>
		<author>Pokharel-S-Lee-CH-Gilyasova-N-et-al-</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[Neuroscreen-1 (NS-1) a sub-clone of pheochromocytoma (PC12) cell is gaining broad acceptance as in vitro neuronal model for biochemical and phenotypic assays due to robust growth and differentiation profiles. However, the molecular characteristics of the cell remains to be documented. In this study, we performed comparative analysis for expression of neuronal marker genes in undifferentiated and nerve growth factor (NGF) differentiated NS-1 and PC12 by qPCR and immunoblot assays. We show that differentiation of NS-1 occurred under low concentrations of NGF relative to PC12. Cell growth also occurred more rapidly in NS-1.  Transcriptional analysis of neuronal marker genes showed comparable expression of tyrosine receptor kinases (Ntrk1, Ntrk2, NGFR/p75NTR) and muscarinic acetylcholine (Chrm1, Chrm2, Chrm3, Chrm4) receptors in unspecialized cells. Ntrk2, adenosine receptors (Adora1, Adora2A) and choline acetyltransferase (ChAT) were altered in undifferentiated NS-1. In contrast, Ntrk1, Ntrk2, Chrm2 transcripts were vastly increased in NS-1 with NGF exposure, while Ntrk3 Adora1 and Adora2A transcripts were reduced. In differentiated PC12, Chrm4 and ChAT were markedly upregulated. Our data suggests that differences in morphological and phenotypic characteristics that distinguish NS-1 from PC12 is likely the product of altered gene expression. Furthermore, expression of neuron type genes in NS-1 support its use as an alternative model to PC12.]]>}</description>
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		<title>Biochemical-Profile-of-Senna-tora-Linn</title>
		<pubDate>26-Feb-2019</pubDate>
<link>http://ijbi.edwiserinternational.com/admin/uploads/16Iqmd.pdf</link>
		<author>Rahul-Gaykhe-Shazeen-Khan-and-Vasant-Kadam</author>
		<comments>{http://www.edwiserinternational.com/contact-us.php}</comments>
		<category>Pharmaceutical Science,Medical Science</category>
		<description>{<![CDATA[The seasonal variation of phenol, tannin and ascorbic acid content have been investigated from leaves, stem, root and seeds of Senna tora. Comparative account of phenol contents of Senna tora showed higher level in leaves (range 5.740 to 6.408 mg/g dry wt.) than stem (range 3.768 to 4.419 mg/g dry wt.), root (range 1.284 to 1.828 mg/g dry wt.) and seeds (3.873 mg/g dry wt). Comparative account of tannin contents of Senna tora showed higher level in leaves (range 0.356 to 0.410 mg/g dry wt.) than stem (range 0.300 to 0.356 mg/g dry wt.), root (range 0.112 to 0.156 mg/g dry wt.) and seeds (2.940 mg/g dry wt.). Comparative account of ascorbic acid contents of Senna tora showed higher level in leaves (range 3.011 to 3.620 mg/g dry wt.) than stem (range 1.988 to 2.612 mg/g dry wt.), root (range 0.970 to 1.109 mg/g dry wt.)  and seeds (2.067 mg/g dry wt.).]]>}</description>
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