Effectiveness of Umbilical Cord Blood Culture vs Peripheral Venous Blood Culture in Diagnosis of Early Onset of Neonatal Sepsis
Volume 5 ; Issue 2 ; in Month : Jul-Dec (2022) Article No : 141
Sha RK, Agarwal M, Bansal R
It has been difficult to identify infant sepsis early in poor countries. The utility of some serum biomarkers that can be used as general indicators of bacterial sepsis include C-reactive protein (CRP), haptoglobin, and fibrinogen, has been questioned due to its low sensitivity. So, comparing the evaluation of EONS via UCB and PBC was the goal of the current study. 88 newborn neonates in all were chosen for our prospective study. Standard laboratory testing was performed, and clinical data were obtained. Blood samples (1 ml) that were aseptically acquired were utilized for both aerobic and anaerobic blood cultures. Using MedCalcs online statistical calculator, the diagnostic test sensitivity and specificity of PCB and UBC were evaluated. 12.5% of clinical sepsis cases had intrapartum antibiotic exposure and that placental chorioamnionitis symptoms were present in 15.27 percent of cases. Only one of the two patients with a single organism UCBC had placental chorioamnionitis verified (Streptococcus anginosus). With sensitivity and specificity, UCBC is a superior approach than venous blood culture for the identification of neonatal sepsis in high-risk neonates. The developed organisms are similar to blood culture samples.
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