Volume 8 ; Issue 1 ; in Month : Jan-June (2025) Article No : 160
Priya SS, Sruthi G, Nandini P, et al.

Abstract

Microorganisms within the human body are integral to numerous health and disease mechanisms. Studies demonstrate that several bacterial species are associated with multiple cancer forms. In addition to its role in cancer start and progression, the microbiome shows potential as a biomarker for cancer diagnosis, risk assessment, and prognosis determination. Intratumoral microorganisms significantly influence tumour biology by governing tumour initiation and progression, as well as altering responses to chemotherapy, radiation, and immunotherapy. A comprehensive understanding of the intratumoral microbiome's function in cancer necessitates additional research into its impacts and underlying mechanisms. This study examines the importance of intratumoral bacteria in cancer start, development, and metastasis, their influence on treatment results, and the methodologies utilized for profiling the intratumoral microbiome.

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