A Validated RP-HPLC Method for Estimation of Telmisartan and Metoprolol in its Bulk Form
Volume 1 ; Issue 2 ; in Month : Apr-Jun (2018) Article No : 110
Suthakaran R, Bikshapathi DVRN, Shankar CH, Prem K
This method is used for the estimation of Metoprolol and Telmisartan present in dosage forms. Chromatogram was performed on Xbridge C18 (5u,4.6x250mm), with a mobile phase composed of methanol: water adjusted pH 3.5 with (58:42% v/v) at flow rate of 1mL/min. the identification was carried out at 224 nm. Parameters studied and reported as in ICH. The linearity range (60-140%) coefficients (0.999) and % recovery was found to be (98-102%).Retention time was (2.091) & (5.089). The test sample in all formulations were within in their label claims and this technique is used for analysis.
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